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Multiple Sclerosis: Medicines for Fatigue

Topic Overview

Medicines used to treat fatigue caused by multiple sclerosis (MS) include:

  • Amantadine. This medicine typically has few side effects. When they do occur, they may include dry mouth, blurred vision, urinary retention, fluid retention, and rash.
  • Fluoxetine (Prozac). This antidepressant may help reduce fatigue in some people who have MS.
  • Modafinil (Provigil). This medicine is used to treat narcolepsy. It has also been used by doctors to treat fatigue in MS.

Related Information

Credits

By Healthwise Staff
Adam Husney, MD - Family Medicine
Anne C. Poinier, MD - Internal Medicine
Barrie J. Hurwitz, MD - Neurology
Last Revised February 15, 2012

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